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PEA protects towards bacterial infection by using innate immune modulation involving MCs, macrophages and microglia. Prophylactic PEA at a dose of 0.one mg/kg physique bodyweight extended survival level and diminished neuro-inflammation within an aged murine bacterial meningitis model, inside the absence of antibiotics [forty two].As a result, inve
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Abstract Long-term agony is An important supply of morbidity for which you'll find constrained productive solutions. Palmitoylethanolamide (PEA), a naturally developing fatty acid amide, has demonstrated utility during the treatment method of neuropathic and inflammatory soreness. Rising reviews have supported a doable position for its use within t